About 1 result found for searched term "TH5427 hydrochloride " (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29453 | TH5427 hydrochloride | DNA/RNA Synthesis |
| TH5427 hydrochloride is a potent, selective NUDT5 inhibitor (IC50=29 nM). TH5427 hydrochloride shows an apparent 690-fold selectivity for NUDT5 over MTH1. TH5427 hydrochloride blocks progestin-dependent, PAR-derived nuclear ATP synthesis and subsequent chromatin remodeling, gene regulation and proliferation in breast cancer cells. | ||
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